Rakish college student Hal (Norman Foster) is in love with sorority girl Peggy (Claudia Dell), but she only has eyes for Hal's roommate Dan (Philips Holmes). Hoping to get Dan out of the way, Hal enlists the aid of campus vamp Patricia (Sylvia Sidney). She manipulates Dan into a hot necking session, resulting in an unscheduled pregnancy. Dan is tossed off the campus, whereupon Peggy pulls off a few dirty tricks of her own, culminating in a shotgun wedding between Hal and Patricia. Finally Dan shows up to do the Honorable Thing by admitting that Patricia's child is his -- not that this is of any help to Hal, who is now persona non grata with everyone concerned. The New York Times reviewer was right on target when he summed up Confessions of a Co-Ed thusly: "The students devote their whole time to discussing affairs of the heart, never for an instant revealing any inclination for work."