Richard Coogan plays a newspaper reporter whose managing editor has been murdered. Accused of the crime, Coogan escapes in order to find the real killer. The trail of evidence leads to a carnival, where several of the performers seem to have strong connections to the town's biggest power brokers. Rosemary Pettit plays Coogan's secretary, who helps to solve the mystery. Filmed in 1961, Girl on the Run should not be confused with the 1957 77 Sunset Strip pilot film of the same title.