Sinclair Lewis's 1920 novel Main Street came to the screen in 1936 from Warner Bros. under this rather more mundane title. Carol Kennicott (Josephine Hutchinson) is the newly-married spouse of small-town doctor William Kennicott (Pat O'Brien). But Carol's big city upbringing hasn't prepared her for life in their rural village, where everyone seems to know everyone else, and everything about them. And the loyal, dedicated physician is so devoted to his patients, that he is oblivious to his wife's growing boredom with their lives, her feelings of emotional claustrophobia, or her seeming attraction to a potential romantic rival (Ross Alexander). Soon the whole town is whispering about the presumed illicit relationship, and the couple's marriage is put to the test.