Writer/director Nancy Savoca, who wrote and directed Household Saints and True Love, handles the same duties in this tale of Grace Santos (Rosie Perez). The producer of a New York City local morning show targeted at women, Grace has an active professional life under the watch of her executive producer, Joan Marshall (Patti LuPone), that already intersects her personal life as she is married to co-host Eddie Diaz (Diego Serrano). When the other co-host, Margo (Karen Duffy), reveals Grace's pregnancy on- air, Joan seizes the opportunity to monitor Grace's development on the show. The ratings grow along with Grace, as the show pursues such topics as "The ABC's of C-Sections" and "You & Your Epidural." While Grace takes comfort in her marriage and her new assistant Madeline (Marianne Jean-Baptiste), who has just returned from six years of raising her young children, Grace worries about the needs of her unborn child versus her much-loved career and Eddie's beckoning film career. Her fears realized through her daughter's first year, Grace must determine what it means to be a "24-Hour Woman."