You cannot keep a good mummy down forever and Kharis is back in this sequel to The Mummy's Hand, which itself was something of a remake of the classic Boris Karloff thriller of 1935, The Mummy. Although assumed to have been killed by Stephen Banning (Dick Foran) in the previous film, Andoheb (George Zucco) has miraculously survived and is now planning a terrible revenge on both Banning and his entire family in Mapleton, MA. With High Priest Mehemet Bey (Turhan Bey) as his faithful companion, Kharis (Lon Chaney Jr.) takes up residence in a Mapleton graveyard where the mysterious Mr. Bey somehow has obtained the job of caretaker. At the first full moon, the mummy is fed enough tanna leaves to break into the Banning residence and kill the now elderly Stephen. To find out what exactly happened, the dead man's son, John (John Hubbard), gets in contact with Babe Hanson (Wallace Ford), one of the members of the original Banning expedition to Egypt. Neither Babe nor John can prevent Kharis from killing Stephen's sister, Jane (Mary Gordon), or from kidnapping John's blonde fiancée, Isobel (Elyse Knox). A posse of upset citizens advances to the graveyard where Mehemet Bey has been promising to literally spend an eternity with Isobel. Interrupted in these romantic pursuits, Bey hands the girl over to Kharis before being shot by John. Carrying a prostrate Isobel, Kharis shuffles back to the Banning estate, which is soon set afire by the mob. Isobel is rescued in the nick of time by John and Kharis perishes in the flames. Or does he?