After divesting himself of his own studio and distribution firm, producer Robert L. Lippert Jr. put together a group of low-budget films for 20th Century-Fox release. Filmed in Mexico, Lippert's Massacre stars Dane Clark as a mounted police officer, sent out to find a group of gun smugglers. Time is of the essence, since the villains are selling guns to the Yaqui Indian tribe, in preparation for an all-out war against the white settlers. Clark is able to destroy the stolen weapons and capture the smugglers, but the Yaquis manage to surround the officer and his prisoners. The outcome of the film is implicit in its title.