The title doesn't refer to mosquitoes but to the amount of money that could be earned in the radio business of the 1930s. Samuel S. Hinds plays a Major Bowes-type entrepreneur who sponsors a weekly radio amateur contest. Hinds' daughter Wendy Barrie has show-biz aspirations, but dad won't hear of it. She enters his contest under an assumed name, winning not only the prize but the heart of a the program's emcee (John Howard).Millions in the Air is one of the few feature films costarring Broadway comedian Willie Howard, whose Jewish characterization and "blue" humor made him difficult to cast in most Hollywood productions.