Warren William stars as Dr. Phillip Wendel Jones, a doctor whose patient dies under questionable circumstances. He is acquitted of murder, but is discredited in the eyes of his community. Dr. Jones settles in another town under an assumed name, where he sets up practice and falls in love with Margaret Stevens (Karen Morley). When his past is revealed, Dr. Jones is rescued from a angry mob by cantankerous old lawyer Anthony Abbott (Lewis Stone). The Outcast is a minor entry given major treatment through the ever-fascinating direction of Robert Florey.