Two Fisted is based on the James Gleason-Richard Taber stage play Is Zat So?, previously filmed under its original title in 1927. Lee Tracy stars as fast-lipped fight manager Hay Hurley, while Roscoe Karns co-stars as slow-witted pugilist Chick Moran. Flat broke, Hay and Chick take servant jobs in the household of wealthy Sue Parker (Gail Patrick). Overstepping their bounds, our heroes manage to dissuade Sue from leaving her husband (Gordon Westcott) and son (Billy Lee) to run off with silly-ass Englishman Fitzstanley (G. P. Huntley Jr.) Grace Bradley is featured as Marie, Hay's dumb-dora girlfriend (suggesting perhaps that her role was originally intended for Gracie Allen).